Scientists have been scrupulously contemplate HIV for decades , but now a new study suggests that the virus can taint and defeat immune cellular telephone in a mode that scientists have so far overlooked .
New Scientist reportsthat new research shows the virus is able kill cells by being pump from one currently infected cell directly into another . All that ’s demand , accord to researchers from the Gladstone Institute of the University of California , San Francisco , is a abbreviated physical connection between the two cells .
The method of transmission is unlike the classic model used to describe the motility of HIV in the body . According to existing thinking , the HIV virus hijacks immune cell known as CD4 MT cells , copy itself using the cadre ’s national mechanism before spreading itself through the descent to pirate more thyroxin cells .
experimentation at the Gladstone Institute , however , show that many of the computer virus particles never actually figure the bloodstream : rather , they ’re pumped like a shot from one thyroxine cell to another through what are known as immunological synapses . What ’s more , the findings suggest that it ’s this sort of transmitting that make the absolute majority of T cubicle death , and not infection by single HIV speck float in the blood .
To what level ? Warner Greene , the lead research worker on the sketch , enjoin New Scientistthat 95 percent of the CD4 thyroxine prison cell he studied died by HIV pumping between cells rather than contagion from blood - borne atom . In fact , he claim that the mental process is likely one C — or even thousands — times more efficient than the Greco-Roman role model of infection . Theresults are published in Cell Reports .
The discover could help shape new treatment for the disease . By better understanding the fashion of transmission , it may be potential to aid slow down the effects of cell - to - cell pumping of HIV , which otherwise leaves triiodothyronine - cadre overwhelmed and unable to cope .
It stay to be seen whether the fresh discovered mode of infection excuse why live HIV discussion do n’t work reliably . But we can be sure of one thing : better apprehension of how the virus spreads can only be a electropositive result in the fight against the disease .
[ Cell ReportsviaNew Scientist ]
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