white-hot light andmystical experiencesare often reported by patients who die and are brought back to sprightliness . Though scientist have never fully been able-bodied to excuse this phenomenon , it has on a regular basis been suggested that it may be because of the liberation of an intensely hallucinogenic particle calledN , N - Dimethyltryptamine(DMT ) during dying . Exactly why this occurs and what function DMT roleplay within the body are presently obscure , although a team of scientists at Debrecen University consider it may bet a vital role in enabling brainiac cells to survive for longsighted menstruum when O is cut off .
Though the squad admit that their hypothesis is based on indirect evidence , conduct researcher Ede Frecska believes that there are enough clues to suggest that this may well be the social occasion of DMT in the consistency . For instance , DMT is among the few internally - produced compounds that bandage to thesigma-1 sensory receptor , which is believed to represent a protective role during a character of cellular tenseness , calledoxidative emphasis , thatcan turn out from a lack of oxygen . Additionally , the fact that the mind has an active intake method which enables the transport of DMT through the blood - mastermind barrier suggests that the organ must involve it for something .
The team has therefore postulated that the role of DMT may be to protect jail cell from oxidative stress , thereby protract the period of prison term they can survive in the absence of oxygen and preventing mind damage . If this hypothesis is confirmed , the research worker consider it could have significant practical applications programme , enable survivor of solidus and heart fire to recover with minimum endangerment of lose their mental capacity .
Having now secured backing for the trial via acrowdfunding campaignthrough platformWalacea , the squad intends to investigate the effect of DMT on oxidative stress in neuronic tissue paper cultures , with the hope of one day progressing to human trial . However , the fact that DMT is sort as aSchedule 1 substanceby the US Drug Enforcement Administration – implying a gamey potential difference for insult and no therapeutic value – may well present a roadblock to research using bouncy topic .
This is in spite of an array of evidencepreviously put forrader by Frecskathat the mote may play a full of life role in immunoregulation . For instance , he suggests that DMT may help to align the resistant responses that fight genus Cancer . This is ground on the fact that the particle ’s synthesis requires an enzyme called indolethylamine - N - methyltransferase ( IMNT ) , which is produced by theimntgene , the construction of which has been find to prevent the recurrence of malignant lung and prostate cancers .
Of the few previous study on DMT , the most famed were the ‘ Spirit Molecule ' experimentation conduct by Rick Strassman of the University of New Mexico in the 1990s . notice that many of his volunteer report deeply mystical experience such as those often associated with demise , he gave the compound its lofty nickname . However , after go to key a practical program for his research , he finally decided to abandon the task . Yet if Frecska ’s supposition is confirmed , we may now finally have a scientific explanation for the blank light that people see on their deathbed .
